This year marks the 32nd anniversary of CHOP Research Poster Day, an annual celebration of the groundbreaking research happening throughout Children's Hospital. This event includes poster presentations from trainees and research staff who will share their exciting discoveries with the CHOP community. Please join us in acknowledging the valuable contributions of the next generation of pediatric scientists and clinicians.
Abstract submission is required for displaying a poster at this event. Please note that we will not be able to accommodate presenters who have not submitted an abstract.
Poster session questions can be directed to the Office of Academic Training and Outreach Programs at ATOP@chop.edu.
The theme of the 2025 symposium is Frontier Programs and will highlight the remarkable breakthroughs achieved over the last decade by CHOP researchers. Mark C. Fishman, MD, Professor of Stem Cell and Regenerative Biology, Harvard University, will provide the first keynote address. William A. Gahl, MD, PhD, Director of the NIH Undiagnosed Diseases Program will provide the second keynote address.
Mark C. Fishman, MD
Professor, Harvard Department of Stem Cell and Regenerative Biology
Mark C. Fishman, MD, is Professor of Stem Cell and Regenerative Biology in the Harvard Faculty of Arts and Sciences, and a cardiologist and founder of the Pathways Clinical Service at the Massachusetts General Hospital (MGH).
Through the first large-scale genetic screen in zebrafish, in the 1990’s Fishman’s lab discovered many of the pathways that guide vertebrate organ development, especially of the heart and vascular system. Additionally, they helped to develop the genomic infrastructure which permitted cloning of the relevant genes, and showed its relevance to human disease and to screening for potential therapeutics. These all helped to make the zebrafish a cornerstone of modern developmental biology.
From 2001-2016, Fishman was the founding President of the Novartis Institutes for BioMedical Research (NIBR), during which time NIBR discovered and brought through successful clinical trials 90 new medicines in more than 120 indications. The approach developed, fousing upon rare and heritable disorders, and introducing what became the first modern cell and gene therapy approved (around CART cell immunotherapy), helped to change pharmaceutical discovery paradigms.
Since returning to Harvard, his research focus has turned to the autonomic nervous system, using the zebrafish to dissect heart-brain interactions at all levels from synapse to behavior. He has, with Professor Melton, inaugurated a new combined Harvard Masters in Biotechnology/MBA program. Fishman is a founder of AditumBio and serves on the Boards of Directors of Beam Therapeutics and Skyline Therapeutics.
Fishman graduated from Yale College and Harvard Medical School, trained in cardiology and was Chief of the Cardiology Division and Director of the Cardiovascular Research Center at Harvard Medical School and the MGH. In addition to his publications in developmental biology and drug discovery, Fishman is the author of the medical textbook, Medicine, and of the book Lab: Building a Home for Scientists, on the history and architectural design of buildings for scientists. Fishman is a member of the National Academy of Medicine and American Academy of Arts and Sciences
William A. Gahl, MD, PhD
Senior Investigator, National Human Genome Research Institute Director of NIH Undiagnosed Diseases Program
Senior Investigator of Medical Genetics Branch
Dr. William A. Gahl graduated from the Massachusetts Institute of Technology and earned his M.D. and Ph.D. from the University of Wisconsin. He served as pediatric resident and chief resident at the University of Wisconsin hospitals and completed clinical genetics and clinical biochemical genetics fellowships at the NIH. Dr. Gahl elucidated the basic defects in cystinosis and Salla disease and helped bring cysteamine to new drug approval by the Food and Drug Administration as the treatment for cystinosis. He has published over 650 papers, reviews, book chapters, and editorials, trained 42 biochemical geneticists and cultivated international experts in Hermansky-Pudlak syndrome, alkaptonuria, Oculocerebrorenal Syndrome of Lowe, Menkes disease, Congenital Disorders of Glycosylation, Griscelli Syndrome, Gray Platelet Syndrome, Joubert Syndrome, polycystic kidney disease and other ciliopathies, Hutchinson-Gilford Progeria, GNE myopathy, oculocutaneous albinism, sialuria, and free sialic acid storage disorders. His group identified the genes responsible for Hartnup disease, Gray Platelet Syndrome, two types of renal Fanconi syndrome, 3-methylglutaconic aciduria type III, a new neutrophil defect, and many other disorders. In 2008, he established the NIH Undiagnosed Diseases Program (UDP), which has made more than 350 rare disease diagnoses and discovered 30 new genetic diseases. Dr. Gahl expanded the UDP to a national Undiagnosed Diseases Network and a worldwide Undiagnosed Diseases Network International. He established American Board of Medical Specialties certification for medical biochemical genetics. Dr. Gahl received the Dr. Nathan Davis Award for Outstanding Government Service from the AMA, the Service to America Medal in Science and the Environment, the EURORDIS Lifetime Achievement Award, and numerous other awards. In 2019, he was elected to the National Academy of Medicine.
The Networking Reception on May 7th, 2025 is generously sponsored by the CHOP Omics & Big Data Initiative.
The CHOP Omics & Big Data Initiative is bringing us closer to our vision to:
Our vision focuses on further developing, accelerating, and optimizing our omics expertise and infrastructure through the accomplishment of six strategic objectives: